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  • Clinically evaluated formulation for eczema-prone skin and scalp

Care that goes beyond symptom relief

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Marigold BioNaturals   is a clinically evaluated, microbiome-active formulation for eczema-prone skin and scalp. It helps calm visible discomfort like itchiness, dryness, and redness, while supporting barrier repair, healthy skin microbiome balance and longer-term skin health.

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Steroid-Free

Maintenance Care

Proprietary Technology

Safety evaluated in kids and adults

For use between flares

Patent Pending

Steroid sparing support

Feel like your skin again.
Powered by microbiome science.

Made with inactivated microbes derived from food and developed through proprietary technology, Marigold BioNaturals is designed to be gentle for kids and adults, with safety and efficacy demonstrated in clinical evaluation.

_________  PRODUCTS (Launching Soon)
 

Two targeted products.
One shared foundation.

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Each product is clinically evaluated, steroid-free, and built for the maintenance phase, the often-overlooked space between acute treatment and basic moisturization.

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Marigold BioNaturals 
For sensitive, eczema-prone skin

A gentle, microbiome-active cream designed for skin that needs more than temporary relief. 

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  • Steroid-free

  • Microbiome‑aware

  • Designed for long‑term maintenance, between flares

  • Helps calm itchiness, dryness, and redness

  • Supports barrier repair and restoration

  • Developed under dermatologist guidance

  • Made with inactivated microbes and soothing oatmeal 

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21% itch comfort improvement in 30 min

57% hydration improvement

91% reduction in overall skin severity

95% satisfaction with continued use

27% itch comfort improvement in 30 min

51% hydration improvement

77% reduction in overall redness severity

100% satisfaction with continued use

Marigold BioNaturals 
For flaky, irritation-prone scalp

A gentle, microbiome-active cream designed for scalp and skin that need more than temporary relief. 

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  • No anti-fungal agents

  • Steroid - free

  • Leave - on care

  • Helps calm flaking, itchiness, and redness

  • Supports a healthier scalp microbiome

  • Designed for maintenance care over time

  • Made with inactivated microbes

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_________  CLINICAL EVIDENCE
 

Safety and efficacy demonstrated in double-blind, randomized, placebo-controlled clinical trials in adults and children with mild to moderate atopic dermatitis (AD).

Early improvement, continued benefits with regular use, and strong user response were seen in clinical evaluation.

For eczema - prone skin cream

At 30 minutes: Comfort begins to improve

 
  • 21% improvement in itch comfort within 30 minutes

  • 57% improvement in hydration

  • 91% improvement in overall skin severity

  • 76% of users reported strong satisfaction

  • Shift towards healthier skin microbiome

  • Evaluated in kids and adults

Before Application

After 30 minutes

After 30 days

After 60 days

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Safety and efficacy demonstrated in double-blind, randomized, placebo-controlled clinical trials in adults with mild to moderate seborrheic dermatitis (SD).

Early improvement, continued benefits with regular use, and strong user response were seen in clinical evaluation.

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Before 

30days

60days

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Before 

30days

60days

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Before 

30days

60days

For flaky irritation prone scalp cream

At 30 minutes: Comfort begins to improve
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  • 27% improvement in itch comfort within 30 minutes
  • 31% reduction in visible flaking

  • 28% reduction in overall redness

  • 100% of users reported continued improvement and willingness to keep using

  • Inflammatory biomarkers shifted

  • Targeted fungal-load decreased

  • As scalp health improved, hair density and thickness showed encouraging signals

  • Follow-up suggested benefits continued even after regular use stopped

© Blossom Microbiotics LLC. All rights reserved.
A North Carolina-based biotechnology company.
These formulations are dermocosmetic products and are not intended to diagnose, treat, cure, or prevent any disease
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